METACHRONOUS CUTANEOUS SQUAMOUS CELL CARCINOMA IN A YOUNG PATIENT AS THE ONLY PRESENTING SYMPTOM TO UNCOVER LYNCH SYNDROME WITH MLH1 GERMLINE MUTATION

Abstract Background Cutaneous malignancies are rare complications of Lynch syndrome and can include Muir-Torre and Turcot syndromes that are associated with sebaceous gland tumors and keratoacanthomas.The incidence and clinical course of cutaneous squamous cell carcinoma have not been well documented in Lynch syndrome due to its rarity.Case present

Recent studies have shown significantly increasing importance of new risk factors such as high levels of homocysteine and C-reactive protein, the presence of thrombophilia Horse Towels markers in the development of stroke.However, information of their relationship in acute defferent types of stroke and acute cardio-vasculares complications caused b

Integrated circuits industry is inherently Collagen linked to the national economy development and the security national defense in China.Its product quality and productivity as bottleneck resolutions are crucially depended on the performance of microelectronic equipment motion platform.However, motion platforms face a series of requirements includ

Objective: The present study has tackled to assess the interaction between lexical-syntactic and prosodic cues of irony, and the fact that how the cues are represented during the production of irony and sarcasm (as one of highly functional irony subtypes) in spontaneous discourse through an auditory modality.Methods: For this purpose, spontaneously

Despite their ecological and social-economic importance, coral reefs are under constant threat and thus require proper management practices.Data on the spatial structure of these ecosystems are essential for good quality conservation projects in such areas.This study aimed to quantitatively analyze the spatial TIE CLIPS distribution of benthic macr